Category Archives: Technology and Society

Health, Technology and Society

Artificial Spleens And Genetic Surgery

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This seems like a big breakthrough, not just for people without spleens, but for iatrogenic disease in hospitals:

To test the device, Ingber and his team infected rats with either E. coli or Staphylococcus aureus and filtered blood from some of the animals through the biospleen. Five hours after infection, 89% of the rats whose blood had been filtered were still alive, compared with only 14% of those that were infected but not treated. The researchers found that the device had removed more than 90% of the bacteria from the rats’ blood. The rats whose blood had been filtered also had less inflammation in their lungs and other organs, suggesting they would be less prone to sepsis.

The researchers then tested whether the biospleen could handle the volume of blood in an average adult human — about 5 litres. They ran human blood containing a mixture of bacteria and fungi through the biospleen at a rate of 1 litre per hour, and found that the device removed most of the pathogens within five hours.

That degree of efficacy is probably enough to control an infection, Ingber says. Once the biospleen has removed most pathogens from the blood, antibiotics and the immune system can fight off remaining traces of infection — such as pathogens lodged in the organs, he says.To test the device, Ingber and his team infected rats with either E. coli or Staphylococcus aureus and filtered blood from some of the animals through the biospleen. Five hours after infection, 89% of the rats whose blood had been filtered were still alive, compared with only 14% of those that were infected but not treated. The researchers found that the device had removed more than 90% of the bacteria from the rats’ blood. The rats whose blood had been filtered also had less inflammation in their lungs and other organs, suggesting they would be less prone to sepsis.

The researchers then tested whether the biospleen could handle the volume of blood in an average adult human — about 5 litres. They ran human blood containing a mixture of bacteria and fungi through the biospleen at a rate of 1 litre per hour, and found that the device removed most of the pathogens within five hours.

That degree of efficacy is probably enough to control an infection, Ingber says. Once the biospleen has removed most pathogens from the blood, antibiotics and the immune system can fight off remaining traces of infection — such as pathogens lodged in the organs, he says.

Note that it could also be effective against ebola.

On another front, eliminating bad proteins using RNA interference.

Faster, please.

Business, Economics, Media Criticism, Political Commentary, Space, Space History, Technology and Society

The SLS Frenzy

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So apparently, the SLF fanbois (and fangirls) going crazy over a giant welder on Twitter.

Anyway, I was rereading this essay I wrote half a decade ago. It was depressing. Here’s how little of some of it I’d have to change to keep it relevant to today.

Continue reading The SLS Frenzy →

Media Criticism, Political Commentary, Popular Culture, Space, Space History, Technology and Society

KSC Versus MSFC

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I had an interesting Twitter discussion this morning, that gave me an insight that had been floating around in the back of my mind, but that I’d never articulated, either to myself or others. It sort of crystallized when someone said that Bob Cabana, head of KSC, was an SLS supporter.

One of the tenets of the Apollo Cargo Cult is that we can’t go beyond earth orbit without a really big rocket. The conventional wisdom has been that the biggest constituency for SLS is Marshall, because that’s were it is being developed. But if you think about it, there are a lot of things Marshall could be applied to — it doesn’t have to be developing big rockets (something it hasn’t successfully done in almost four decades). For instance, it could be developing technology and demonstrators for orbital fuel storage and transfer. That would be at least as much in its wheelhouse as SLS.

KSC, on the other hand, has little justification for existence if NASA doesn’t have its own (big) rocket to launch. Without a big rocket, it doesn’t need the VAB, and the VAB and the crawler are really the only unique capability it has, in terms of physical infrastructure. If everything is going up on commercial rockers, even from Pads 39, KSC doesn’t have much to do, other than integrating NASA’s payloads onto them. That’s not a trivial task, but it’s not one that justifies the center’s budget or workforce. So, while Marshall could in theory be redirected to something useful, KSC can’t really. That’s why Nelson supports it so strongly.

It struck me in fact that the VAB is the high cathedral for the cargo cult. What would happen to the religion if it was taken out by a hurricane?