Alzheimer’s may be a third form of diabetes.

“Insulin disappears early and dramatically in Alzheimer’s disease. And many of the unexplained features of Alzheimer’s, such as cell death and tangles in the brain, appear to be linked to abnormalities in insulin signaling. This demonstrates that the disease is most likely a neuroendocrine disorder, or another type of diabetes,” says researcher Suzanne M. de la Monte, professor of pathology at Brown Medical School, in a news release.

If so, that might provide some clues to treating it.