If H5N1 is so lethal, it might be a justifiable move on utilitarian grounds to manufacture and release H5N2 or something so people with partial immunity to the most common variants could obtain partial immunity to H5N1. That would probably not be condoned because the idea of killing tens of thousands to innoculate and thereby protect millions who would otherwise die in an H5N1 pandemic is morally and politically dead on arrival (pun intended). If we can’t stomach 2,000 dead in Iraq, there are many high utility strategies that are not options. This one can be pursued, however, by a determined minority.