These recommendations are far too non-quantitative for me to have any idea what to make of them.
6 thoughts on “New Vitamin D Guidelines”
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These recommendations are far too non-quantitative for me to have any idea what to make of them.
Comments are closed.
Massive doses of Vitamin D have some caveats: You need some extra Vitamin K and the big one is that it can increase the chances of blood clots(!) so taking some baby aspirin along with it is prudent.
What are you calling “massive”? This comment is as useless as the article.
Cannot get an LD50 number for Vitamin D. Probably some damn ethical something or other having to do with people. But that bastion of medical knowledge Wikipedia says:
Acute overdose requires between 15,000 μg/d (600,000 IU per day) and 42,000 μg/d (1,680,000 IU per day) over a period of several days to months.
So you have an upper bound. Give or take.
Well, that’s several orders of magnitude more than I take.
Oh I left out the Comparative Toxicity Report:
Comparative Toxicity: Use of Vitamin D in Rodenticides
Further information: Rodenticide § Hypercalcemia
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D’s toxic effects in humans.
Concentrations used in these rodenticides are several orders of magnitude higher than the maximum recommended human intake, with acute baits containing 3,000,000 IU/g for D3 and 4,000,000 IU/g for D2. This leads to hypercalcemia in the rodents and subsequent death several days after ingestion.[45][46]
I’d stay below those dosages, or any rodenticide that tastes like chicken.
There are no guidelines there – in fact, the statement recommending AGAINST testing blood levels because they don’t know what is good is just what we’ve come to expect from the government.
The RDA levels are based on 95% of the population not showing frank signs of deficiency: Nothing about good, better, best, optimal, dangerous.
It seems that the IoM should actually STUDY the effect of various levels.
Personally, I take ~17,500 iu daily and it keeps my blood levels (based on annual blood testing) at around 80-85ng/dl. Which works for me.